Medicare increasingly views sepsis as one of the most important areas of health care policy, and this is more acute in 2020, since many COVID-19 patients die in septic shock. Medicare uses a complex quality measure, called "SEP-1," which presents challenges for hospitals and has had mixed responses in the peer-reviewed literature. Meanwhile, discussion is turning other measures of care quality and expanded use of biomarkers to guide care in sepsis. This webinar will overview the prevalence of sepsis in the Medicare population, review the SEP-1 measure, and discuss new trends in quality measures in sepsis.